Markku Mäki Selected Research

Protein Glutamine gamma Glutamyltransferase 2

10/2021	A Trial of a Transglutaminase 2 Inhibitor in Celiac Disease. Reply.
1/2021	A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease.
10/2017	Accuracy in Diagnosis of Celiac Disease Without Biopsies in Clinical Practice.
1/2017	Anemia in Pediatric Celiac Disease: Association With Clinical and Histological Features and Response to Gluten-free Diet.
4/2015	Celiac disease autoimmunity and hip fracture risk: findings from a prospective cohort study.
8/2014	Early microbial markers of celiac disease.
4/2014	Celiac disease patient IgA antibodies induce endothelial adhesion and cell polarization defects via extracellular transglutaminase 2.
3/2013	Prospective antibody case finding of coeliac disease in type-1 diabetes children: need of biopsy revisited.
1/2013	Thioredoxin is involved in endothelial cell extracellular transglutaminase 2 activation mediated by celiac disease patient IgA.
1/2013	Celiac Disease-Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics.

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Markku Mäki Research Topics

Disease

90	Celiac Disease (Celiac Sprue) 12/2021 - 01/2002
20	Atrophy 12/2019 - 03/2002
8	Inflammation (Inflammations) 01/2017 - 03/2009
7	Anemia 01/2021 - 04/2013
5	Hyperplasia 01/2017 - 09/2010
4	Dermatitis Herpetiformis (Disease, Duhring's) 02/2019 - 07/2004
4	Dyspepsia (Indigestion) 05/2018 - 03/2010
3	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 12/2019 - 06/2003
3	Ataxia (Dyssynergia) 02/2019 - 10/2010
3	Neoplasms (Cancer) 06/2017 - 01/2006
3	Crohn Disease (Crohn's Disease) 01/2009 - 03/2002
2	Infections 01/2020 - 01/2019
2	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 01/2015
2	Metabolic Bone Diseases (Osteopenia) 06/2017 - 01/2015
2	Genetic Predisposition to Disease (Genetic Predisposition) 01/2014 - 01/2002
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 03/2013 - 04/2009
2	Liver Diseases (Liver Disease) 01/2006 - 04/2002
2	Epilepsy (Aura) 08/2005 - 05/2005
1	Injection Site Reaction 12/2019
1	Intestinal Diseases (Diseases, Intestinal) 02/2019
1	Malabsorption Syndromes (Malabsorption Syndrome) 01/2019
1	Failure to Thrive 01/2019
1	Osteoporosis 06/2017
1	IgA Deficiency 12/2016
1	Primary Immunodeficiency Diseases 12/2016
1	Type 2 Diabetes Mellitus (MODY) 07/2016
1	Hip Fractures (Intertrochanteric Fractures) 04/2015
1	Diarrhea 01/2015
1	Weight Gain 01/2015
1	Movement Disorders (Movement Disorder) 05/2013
1	Iron Deficiencies 12/2011
1	Neurologic Manifestations (Neurological Manifestations) 06/2011
1	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 03/2011
1	Acquired Immunodeficiency Syndrome (AIDS) 03/2011
1	Hypersensitivity (Allergy) 10/2010

Drug/Important Bio-Agent (IBA)

45	Glutens (Glutelin)IBA 01/2021 - 03/2003
32	AntibodiesIBA 01/2021 - 03/2002
29	Protein Glutamine gamma Glutamyltransferase 2IBA 10/2021 - 03/2002
23	Immunoglobulin A (IgA)IBA 10/2017 - 04/2002
20	AutoantibodiesIBA 01/2017 - 06/2003
11	TransglutaminasesIBA 01/2017 - 05/2005
6	GliadinIBA 01/2013 - 02/2008
4	Peptides (Polypeptides)IBA 01/2021 - 03/2008
4	Immunoglobulin G (IgG)IBA 01/2015 - 05/2005
4	Proteins (Proteins, Gene)FDA Link 09/2014 - 06/2003
4	AntigensIBA 08/2014 - 03/2002
4	HLA Antigens (Human Leukocyte Antigens)IBA 03/2012 - 03/2002
4	AutoantigensIBA 01/2012 - 09/2010
3	Peptide Hydrolases (Proteases)FDA Link 01/2017 - 01/2009
3	Hemoglobins (Hemoglobin)IBA 01/2017 - 01/2017
3	IronIBA 01/2017 - 05/2005
3	HLA-DQ Antigens (HLA-DQ)IBA 01/2008 - 01/2002
2	Formaldehyde (Formol)FDA Link 12/2021 - 10/2021
2	ParaffinIBA 12/2021 - 10/2021
2	EnzymesIBA 01/2021 - 11/2008
2	Biomarkers (Surrogate Marker)IBA 12/2018 - 02/2013
2	ALV003IBA 01/2017 - 06/2014
2	AlbuminsIBA 01/2017 - 01/2017
2	Ferritins (Ferritin)IBA 01/2017 - 12/2011
2	Immunoglobulins (Immunoglobulin)IBA 01/2015 - 08/2005
2	Membrane Proteins (Integral Membrane Proteins)IBA 08/2014 - 09/2008
2	Pharmaceutical PreparationsIBA 12/2012 - 07/2012
2	Fatty Acids (Saturated Fatty Acids)IBA 03/2011 - 01/2009
1	apolipoprotein A-IV (apolipoprotein AIV)IBA 01/2021
1	Chemokine ReceptorsIBA 01/2021
1	ChemokinesIBA 01/2021
1	ZED1227IBA 01/2021
1	LigandsIBA 01/2021
1	Glutamine (L-Glutamine)FDA Link 01/2021
1	Amino Acids FDA Link 01/2020
1	Cysteine (L-Cysteine)FDA Link 01/2020
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020
1	Arachidonic Acid (Vitamin F)IBA 01/2020
1	Glutamic Acid (Glutamate)FDA Link 01/2020
1	AMG-714IBA 12/2019
1	VaccinesIBA 01/2019
1	Antidepressive Agents (Antidepressants)IBA 05/2018
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 12/2017
1	Polycomb Repressive Complex 2IBA 01/2017
1	Transferrin (beta 2 Transferrin)IBA 01/2017
1	Transferrin Receptors (Transferrin Receptor)IBA 01/2017
1	Alanine Transaminase (SGPT)IBA 09/2016
1	TransferasesIBA 04/2015
1	Vitamin D FDA LinkGeneric 04/2015
1	HLA-DQ8 antigenIBA 01/2014
1	Peptide LibraryIBA 11/2013
1	EpitopesIBA 11/2013
1	Simvastatin (Zocor)FDA LinkGeneric 08/2013
1	16S Ribosomal RNAIBA 04/2013
1	ThioredoxinsIBA 01/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 09/2012
1	Small Interfering RNA (siRNA)IBA 07/2012
1	RNA (Ribonucleic Acid)IBA 03/2012
1	Transaminases (Aminotransferases)IBA 09/2011
1	UbiquitinIBA 06/2011
1	GoldIBA 03/2011
1	Polysaccharides (Glycans)IBA 02/2011
1	Galactose (Galactopyranose)FDA LinkGeneric 02/2011
1	galactosyl-deficient IgA1IBA 02/2011

Therapy/Procedure

36	Gluten-Free Diet 01/2021 - 03/2002